The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2017

Filed:

Feb. 08, 2013
Applicant:

The Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Xiaodong Cheng, League City, TX (US);

Jia Zhou, League City, TX (US);

Tamara Tsalkova, Galveston, TX (US);

Fang Mei, League City, TX (US);

Haijun Chen, Gelveston, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/513 (2006.01); A61K 31/42 (2006.01); A61K 31/4709 (2006.01); A61K 45/06 (2006.01); A61K 31/136 (2006.01); A61K 31/10 (2006.01); A61K 31/277 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
A61K 31/513 (2013.01); A61K 31/10 (2013.01); A61K 31/136 (2013.01); A61K 31/277 (2013.01); A61K 31/42 (2013.01); A61K 31/4709 (2013.01); A61K 31/505 (2013.01); A61K 45/06 (2013.01);
Abstract

Embodiments of the invention are directed to compounds that inhibit an activity of EP AC proteins and methods of using the same. The inventors have developed a sensitive and robust high throughput screening (HTS) assay for the purpose of identifying EPAC specific inhibitors (Tsalkova et al. (2012) PLOS ONE 7(1):e30441).


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