The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2017
Filed:
Sep. 06, 2013
The Governors of the University of Alberta, Edmonton, CA;
Medizinische Hochschule Hannover, Hannover, DE;
Abdolamir Landi, Edmonton, CA;
Michael Houghton, Edmonton, CA;
D. Lorne Tyrrell, Edmonton, CA (US);
Tim Lankisch, Hannover, DE;
Tobias Weismueller, Hannover, DE;
Michael Manns, Isernhagen, DE;
The Governors of the University of Alberta, Edmonton, CA;
Medizinische Hochschule Hannover, Hannover, DE;
Abstract
The present disclosure provides methods and compositions that find use in facilitating a diagnosis of inflammatory liver disease in a subject. The methods and compositions generally involve detection of eotaxin-3 (E3) levels, either alone or with levels of eotaxin-1 (E1), and optionally, with levels of CCL22 and, further optionally, with levels of IL15. These levels can be used to facilitate a diagnosis of a liver disease of at least one of autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC), and/or to facilitate a differential diagnosis between AIH, PBC, and PSC. The methods and compositions of the present disclosure also find use in facilitating treatment decisions for a subject.