The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2017

Filed:

Jan. 10, 2009
Applicants:

Martin L. Yarmush, Newton, MA (US);

Robert Freedman, Beverly Hills, CA (US);

Aurelia Del Bufalo, Paris, FR;

Silvia Teissier, Rueil Malmaison, FR;

Jean-roch Meunier, Aulnay sous Bois, FR;

Inventors:

Martin L. Yarmush, Newton, MA (US);

Robert Freedman, Beverly Hills, CA (US);

Aurelia Del Bufalo, Paris, FR;

Silvia Teissier, Rueil Malmaison, FR;

Jean-Roch Meunier, Aulnay sous Bois, FR;

Assignee:

L'OREAL, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); G01N 33/50 (2006.01); C12M 3/06 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/505 (2013.01); C12M 23/16 (2013.01); C12M 23/58 (2013.01); G01N 33/5044 (2013.01);
Abstract

Devices and methods are provided for detecting an immune reaction to a test agent using an immune modeling system comprising a barrier component configured to culture a biological barrier, an immune component configured to culture immune cells, and one or more inter-component microfluidic connections between the barrier component and the immune component. The system provides for culturing a biological barrier in the barrier component of the system, culturing immune cells in the immune component of the system, applying the test agent to the biological barrier, and monitoring the immune cells to detect an immune reaction to the test agent.


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