The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2017
Filed:
Aug. 07, 2013
Applicant:
Nestec S.a., Vevey, CH;
Inventors:
Sharat Singh, Rancho Santa Fe, CA (US);
Xinjun Liu, San Diego, CA (US);
Kelly D. Hester, San Diego, CA (US);
Assignee:
NESTEC S.A., Vevey, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/49 (2006.01); G01N 1/40 (2006.01); A61M 1/02 (2006.01); A61M 1/34 (2006.01); B01L 3/00 (2006.01); A61M 1/36 (2006.01);
U.S. Cl.
CPC ...
G01N 33/491 (2013.01); A61M 1/029 (2013.01); A61M 1/3496 (2013.01); B01L 3/5021 (2013.01); G01N 1/4077 (2013.01); A61M 1/02 (2013.01); A61M 1/3633 (2013.01); A61M 2202/0439 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0681 (2013.01); G01N 2001/4088 (2013.01);
Abstract
The present invention provides novel apparatuses and methods for isolating or recovering a subset of blood cells such as leukocytes and/or circulating tumor cells from blood samples by filtration without changing the intracellular concentration of a therapeutic agent such as an anticancer drug. Contrary to the art, the apparatuses and methods of the present invention advantageously provide cell lysates from recovered cells such as leukocytes and/or circulating tumor cells without substantial dilution of a therapeutic agent such as an anticancer drug.