The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9534999 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 03, 2017

Filed:

Jun. 17, 2013
Applicant:

Ellen T. Chen, Germantown, MD (US);

Inventor:

Ellen T. Chen, Germantown, MD (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 15/10 (2006.01); B82Y 30/00 (2011.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
G01N 15/1031 (2013.01); G01N 27/3278 (2013.01); A61B 5/0091 (2013.01); B82Y 30/00 (2013.01); G01N 2015/1006 (2013.01); G01N 2610/00 (2013.01); G01N 2800/7028 (2013.01);
Abstract

The present invention provides a single cancer direct detection device comprises an electrode having a nanopore biomimetic membrane inducing a bio-communication signal by cancer cells selectively under antibody-free and label-free condition. Methods of detecting cancer cells and monitoring cancer progresses in a contour map format are also discussed. In particular, the cancer cell heat release map comprises multiple variables correlations, a ratio of 'Action potential/Resting potential' (RAPRP) as a special biomarker for the variable along with other variables of current or concentration makes visual display cancer progresses possible compared with normal cells which have negligible heat release.


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