The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2017

Filed:

Feb. 07, 2014
Applicants:

John P. Marino, Silver Spring, MD (US);

Zvi Kelman, Gaithersburg, MD (US);

Jerard Hurwitz, New York, NY (US);

Gary G. Giulian, Gaithersburg, MD (US);

Inventors:

John P. Marino, Silver Spring, MD (US);

Zvi Kelman, Gaithersburg, MD (US);

Jerard Hurwitz, New York, NY (US);

Gary G. Giulian, Gaithersburg, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12P 19/32 (2006.01); C07H 19/10 (2006.01); C07H 19/207 (2006.01); C12P 19/30 (2006.01);
U.S. Cl.
CPC ...
C12P 19/32 (2013.01); C07H 19/10 (2013.01); C07H 19/207 (2013.01); C12P 19/305 (2013.01); C12Y 207/07 (2013.01); Y02P 20/52 (2015.11);
Abstract

A process for making a nucleotide analog includes combining a first substrate that includes a linker and a base with a second substrate to form a substrate composition. An enzyme contacts the substrate composition and catalyzes formation of the nucleotide analog from the first substrate and the second substrate. Additionally, a composition includes the first substrate, second substrate, the enzyme, the nucleotide analog, and optional additives.


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