The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2017

Filed:

Jun. 13, 2013
Applicant:

Dow Agrosciences Llc, Indianapolis, IN (US);

Inventors:

Matthew Kelker, Zionsville, IN (US);

Aaron T. Woosley, Fishers, IN (US);

Assignee:

Dow AgroSciences LLC, Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/64 (2006.01); C12N 15/11 (2006.01); C12N 15/63 (2006.01); C12N 15/78 (2006.01); C12P 21/00 (2006.01); C12N 1/21 (2006.01); C12N 15/67 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12N 15/63 (2013.01); C12N 15/64 (2013.01); C12N 15/78 (2013.01); C12P 21/00 (2013.01); C12N 2310/353 (2013.01);
Abstract

Compositions and methods for improving expression of a recombinant protein or polypeptide of interest in a host cell are provided. Compositions comprising a polynucleotide coding sequence for a BTBooster are provided using a plant optimized system. The coding sequences can be used in vector constructs or expression systems for transformation and expression of a recombinant protein or polypeptide of interest in a host cell. Methods comprising the codon optimization of a polynucleotide coding sequence for increased expression in a bacterial host are provided. The codon optimization method can be used in designing a polynucleotide coding sequence which expresses robust levels of protein in a bacterial host cell.


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