The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2017
Filed:
May. 18, 2012
Lluis Solà Carandell, Tarragona, ES;
Jordi Cerón Bertran, Tarragona, ES;
Glòria Freixas Pascual, Tarragona, ES;
Pere Dalmases, Barcelona, ES;
Lluis Solà Carandell, Tarragona, ES;
Jordi Cerón Bertran, Tarragona, ES;
Glòria Freixas Pascual, Tarragona, ES;
Pere Dalmases, Barcelona, ES;
Laboratorios Lesvi S.L., Barcelona, ES;
Abstract
A monoclinic crystalline form of asenapine maleate is described, which is characterized in that it is not micronised and has a particle size distribution characterized by a d90 of 40 μm or less. A process for the preparation of a monoclinic crystalline form of asenapine maleate is also described, the process comprising the following steps: a) providing a mixture of monoclinic asenapine maleate and an organic solvent which, under the conditions of the process, acts as an antisolvent; b) stirring the mixture at a temperature between 15 and 60° C.; and c) collecting the crystals, wherein the organic solvent is selected from alcohols, ketones, ethers, esters, hydrocarbons or mixtures thereof.