The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2017

Filed:

Nov. 13, 2013
Applicant:

Asana Biosciences, Llc, Bridgewater, NJ (US);

Inventors:

Roger A. Smith, Chester Springs, PA (US);

Nicholas James Laping, Malvern, PA (US);

Aranapakam M. Venkatesan, Malvern, PA (US);

Raghava Reddy Kethiri, Noida, IN;

Chandregowda Venkateshappa, Noida, IN;

Bheemashankar Kulkarni, Noida, IN;

Purushottam Dewang, Noida, IN;

Rajendra Kristam, Noida, IN;

Rajesh Devraj, Noida, IN;

Assignee:

Asana BioSciences, LLC, Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4965 (2006.01); C07D 401/14 (2006.01); C07D 213/30 (2006.01); C07D 417/06 (2006.01); C07D 213/84 (2006.01); C07D 401/06 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/06 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 417/06 (2013.01); C07D 213/30 (2013.01); C07D 213/84 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/06 (2013.01); C07D 417/14 (2013.01);
Abstract

The present application provides novel pyridine compounds and pharmaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CYP17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.


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