The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2017
Filed:
Aug. 20, 2014
Applicants:
Andrew Kung, Walpole, MA (US);
David Ziegler, Dover Heights, AU;
Inventors:
Andrew Kung, Walpole, MA (US);
David Ziegler, Dover Heights, AU;
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/02 (2006.01); A61K 31/496 (2006.01); G01N 33/50 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/02 (2013.01); A61K 31/496 (2013.01); A61K 45/06 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5044 (2013.01); G01N 33/57484 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7028 (2013.01);
Abstract
The present invention features a method for determining the prognosis for survival of a cancer patient. Methods for measuring the level of NOL3 expression in a cancer cell-containing sample from a patient, and comparing the level of NOL3 expression in the sample to a reference level of NOL3 expression are also included. A higher level of NOL3 relative to the reference level correlates with decreased survival of the patient, and an equivalent or lower level of NOL3 relative to the reference level correlates with increased survival of the patient.