logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9533973 B1

PDFFull Text
Date of Patent:
Jan. 03, 2017

Filed:

Dec. 07, 2012

Allosteric modulators of 5-hydroxytryptamine 2c receptor (5-ht2cr)

Applicant:

The Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Jia Zhou, League City, TX (US);

Chunyong Ding, Galveston, TX (US);

Kathryn A. Cunningham, Galveston, TX (US);

Assignee:

THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);

Attorney:

Norton Rose Fulbright US LLP

Primary Examiner:

Celia Chang

Int. Cl.
CPC ...
C07D 211/32 (2006.01); C07D 405/12 (2006.01); C07D 223/16 (2006.01); C07D 241/04 (2006.01); C07D 211/34 (2006.01); C07D 211/60 (2006.01); C07H 15/14 (2006.01); C07H 15/16 (2006.01); C07D 309/10 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); C07D 211/32 (2013.01); C07D 211/34 (2013.01); C07D 211/60 (2013.01); C07D 223/16 (2013.01); C07D 241/04 (2013.01); C07D 309/10 (2013.01); C07H 15/14 (2013.01); C07H 15/16 (2013.01);
Abstract

The disclosure is directed to compounds identified as allosteric modulators of 5-HT 2CR, as well as pharmaceutical compositions and methods using the same. Certain embodiments also include methods of identifying and methods of synthesizing the compounds. Optimization and development of allosteric 5-HT 2CR modulators that bind sites other than the primary ligand binding site generate novel, highly selective, and potent ligands of 5-HT2CR. Such molecules can be used as small molecule probes for the nervous system and as effective therapeutics for a variety of diseases.

Find Patent Forward Citations

Zhou, Jia. (2017). Allosteric modulators of 5-hydroxytryptamine 2c receptor (5-ht2cr) (U.S. Patent No. 9533973). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9533973

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…