The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2017

Filed:

Jun. 07, 2016
Applicant:

Takeda Pharmaceutical Company Limited, Chuo-ku, Osaka-shi, Osaka, JP;

Inventors:

Toshitake Kobayashi, Kanagawa, JP;

Morihisa Saitoh, Kanagawa, JP;

Yasufumi Wada, Kanagawa, JP;

Hiroshi Nara, Kanagawa, JP;

Nobuyuki Negoro, Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 317/72 (2006.01);
U.S. Cl.
CPC ...
C07D 317/72 (2013.01);
Abstract

The present invention provides compounds having a Toll-like receptor 4 (TLR4) signaling inhibitory action useful as preventive and therapeutic drugs of inflammatory disease and/or central nervous system disease or diseases such as chemotherapy-induced peripheral neuropathy (CIPN), chemotherapy-induced neuropathic pain (CINP), liver injury, ischemia-reperfusion injury (IRI) and the like. The present invention relates to a compound represented by formula (I) and a salt thereof: (wherein, each symbol is explained in greater detail in the specification).


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