The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2017
Filed:
Jan. 14, 2013
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Cisen Pharmaceutical Co., Ltd., Jining, CN;
Chunhao Yang, Shanghai, CN;
Zehong Miao, Shanghai, CN;
Jian Ding, Shanghai, CN;
Meng Wang, Shanghai, CN;
Jinxue He, Shanghai, CN;
Cun Tan, Shanghai, CN;
Yi Chen, Shanghai, CN;
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, Shanghai, CN;
CISEN PHARMACEUTICAL CO., LTD., Jining, CN;
Abstract
Provided in the present invention are a 2-arylbenzofuran-7-formamide compound as shown in general formula I or a pharmacologically or physiologically acceptable salt thereof, a preparation method thereof and use thereof in preparing anti-tumour drugs, wherein Rand Rare each independently hydrogen, straight or branched chained C-Calkyl, C-Ccycloalkyl or saturated 5- or 6-membered heterocyclyl containing oxygen or nitrogen; or Rand Rtogether with N form an unsubstituted or substituted saturated 5- or 6-membered heterocyclyl containing at least one heteroatom, wherein the heteroatom is O, N and S, the substituent is a methyl on N; Ris a hydrogen atom or a chlorine atom; Ris a hydrogen atom or a fluorine atom; X is CH, CF or N; and Y is CH, CF or N.