The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2017
Filed:
Apr. 03, 2013
Applicant:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Inventors:
Pekka Katajisto, Cambridge, MA (US);
Michael Pacold, Boston, MA (US);
David M. Sabatini, Cambridge, MA (US);
Omer Yilmaz, Ann Arbor, MI (US);
Assignee:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/675 (2006.01); A61K 45/06 (2006.01); A61K 31/436 (2006.01); A61K 31/7076 (2006.01); A61K 31/7088 (2006.01); A61K 38/46 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
A61K 31/675 (2013.01); A61K 31/436 (2013.01); A61K 31/7076 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 38/46 (2013.01); A61K 45/06 (2013.01); C12Y 301/00 (2013.01);
Abstract
Disclosed herein are novel methods and compositions useful for promoting intestinal stem cell function. The methods and compositions are particularly useful for stimulating the proliferation of and/or self-renewal of intestinal stem cells, as well as for minimizing, preventing, or ameliorating cellular damage resulting from incidental or accidental exposure to radiation (e.g., cancer radiation therapy).