The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2017

Filed:

Aug. 27, 2015
Applicant:

Targacept, Inc., Winston-Salem, NC (US);

Inventors:

Srinivasa Rao Akireddy, Winston-Salem, NC (US);

Balwinder Singh Bhatti, Winston-Salem, NC (US);

Ronald Joseph Heemstra, Lewisville, NC (US);

Matt S. Melvin, Winston-Salem, NC (US);

Jason Speake, Winston-Salem, NC (US);

Yunde Xiao, Clemmons, NC (US);

Daniel Yohannes, Winston-Salem, NC (US);

Assignee:

Targacept, Inc., Winston-Salem, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/13 (2006.01); A61K 31/40 (2006.01); C07C 211/38 (2006.01); C07C 211/41 (2006.01); C07D 205/04 (2006.01); C07D 295/033 (2006.01); A61K 31/397 (2006.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61K 31/13 (2013.01); A61K 31/397 (2013.01); C07C 211/38 (2013.01); C07C 211/41 (2013.01); C07D 205/04 (2013.01); C07D 295/033 (2013.01);
Abstract

The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.


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