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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9532957 B1

PDFFull Text
Date of Patent:
Jan. 03, 2017

Filed:

Mar. 05, 2014

[object object]

Applicant:

Kaneka Corporation, Osaka, JP;

Inventors:

Takahiro Ueda, Takasago, JP;

Tadao Ono, Takasago, JP;

Mitsutoshi Moro, Takasago, JP;

Shiro Kitamura, Takasago, JP;

Yasuyoshi Ueda, Takasago, JP;

Assignee:

KANEKA CORPORATION, Osaka, JP;

Attorney:

Polsinelli PC

Primary Examiner:

Thane Underdahl

Int. Cl.
CPC ...
A61K 31/122 (2006.01); A61K 47/10 (2006.01); A61K 47/12 (2006.01); A61K 47/14 (2006.01); A61K 47/22 (2006.01); B01D 9/00 (2006.01); C07C 41/26 (2006.01); C07C 41/40 (2006.01); C07C 41/46 (2006.01); C07C 43/23 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/122 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/14 (2013.01); A61K 47/22 (2013.01); B01D 9/00 (2013.01); C07C 41/26 (2013.01); C07C 41/40 (2013.01); C07C 41/46 (2013.01); C07C 43/23 (2013.01); A61K 9/4866 (2013.01);
Abstract

The present invention provides a stabilization method, a preservation method and the like method of reduced coenzyme Q, which is useful as functional nutritive foods, specific health foods and the like. Furthermore, the present invention provides a method for efficiently obtaining reduced coenzyme Qof high quality and by a method suitable for a commercial production. It is possible to handle and stably preserve reduced coenzyme Qunder a condition that oxidation by a molecular oxygen is inhibited by contacting reduced coenzyme Qwith, an ascorbic acid and citric acid or a related compound thereof, and thus a stabilized composition is obtained. Moreover, reduced coenzyme Qis converted into a crystalline state in such a condition that the formation of oxidized coenzyme Qas a byproduct is minimized by crystallizing reduced coenzyme Qin the presence of ascorbic acid or a related compound thereof etc., and thus a reduced coenzyme Qcrystal of high quality is produced. Furthermore, by successively crystallizing the generated reduced coenzyme Qin the presence of ascorbic acid or related compound thereof after reducing oxidized coenzyme Qto reduced coenzyme Qusing ascorbic acid or a related compound thereof, operations are simplified and minimized, and thus reduced coenzyme Qof high quality is produced.

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