The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2016

Filed:

Dec. 14, 2012
Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Christopher Fang-Yen, Philadelphia, PA (US);

Gabriel Popescu, Champaign, IL (US);

Changhuei Yang, Pasadena, CA (US);

Adam Wax, Chapel Hill, NC (US);

Ramachandra Dasari, Shererville, IN (US);

Michael Feld, Jamaica Plain, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01B 11/02 (2006.01); G01B 9/02 (2006.01); A61B 5/1455 (2006.01); G01N 21/45 (2006.01); A61B 5/145 (2006.01); A61B 5/00 (2006.01); G01J 9/04 (2006.01);
U.S. Cl.
CPC ...
G01B 9/02091 (2013.01); A61B 5/1455 (2013.01); G01B 9/02002 (2013.01); G01B 9/02007 (2013.01); G01B 9/0209 (2013.01); G01B 9/02011 (2013.01); G01B 9/02057 (2013.01); G01B 9/02063 (2013.01); G01B 9/02067 (2013.01); G01B 9/02069 (2013.01); G01B 9/02071 (2013.01); G01B 9/02072 (2013.04); G01B 9/02078 (2013.01); G01B 9/02083 (2013.01); G01N 21/45 (2013.01); A61B 5/14532 (2013.01); A61B 5/7232 (2013.01); G01B 2290/45 (2013.01); G01B 2290/60 (2013.01); G01B 2290/70 (2013.01); G01J 9/04 (2013.01);
Abstract

Preferred embodiments of the present invention are directed to systems for phase measurement of biological materials which can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at the sub-micron level which can include, without limitation, imaging origins of dysplasia, cellular communication, neuronal transmission and implementation of the genetic code. The structure and dynamics of sub-cellular constituents cannot be currently studied in their native state using the existing methods and technologies including, for example, x-ray and neutron scattering.


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