The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
Nov. 14, 2014
Prosensa Technologies B.v., Leiden, NL;
Academisch Ziekenhuis Leiden, Leiden, NL;
Josephus Johannes De Kimpe, Utrecht, NL;
Adriana Marie Rus, Hoofddorp, NL;
Gerard Johannes Platenburg, Voorschoten, NL;
Judith Christina Theodora Van Deutekom, Dordrecht, NL;
Garrit-Jan Boudewijn Van Ommen, Amsterdam, NL;
BioMarin Technologies B.V., Leiden, NL;
Academisch Ziekenhuis Leiden, Leiden, NL;
Abstract
The invention relates to a method for inducing or promoting skipping of exon 45 of DMD pre-mRNA in a Duchenne Muscular Dystrophy patient, preferably in an isolated (muscle) cell, the method comprising providing an isolated muscle cell with a molecule that binds to a continuous stretch of at least 21 nucleotides within the exon. The invention further relates to such molecule used in the method.