The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
Jul. 25, 2013
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Joseph Cuiffi, Fort Myers, FL (US);
Jeffrey T. Borenstein, Newton, MA (US);
Anilkumar Harapanahalli Achyuta, Tampa, FL (US);
Mark J. Mescher, West Newton, MA (US);
Linda Griffith, Cambridge, MA (US);
Samuel Walker Inman, Boston, MA (US);
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
The Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of tissue types in a biomimetic environment. By culturing organ specific tissue types within a biomimetic environment and interconnecting each of the organ systems in a physiologically meaningful way, experiments can be conducted on in vitro cells that substantially mimic the responses of in vivo cell populations. In some implementations, the system is used to monitor how organ systems respond to agents such as toxins or medications. The system enables the precise and controlled delivery of these agents, which, in some implementations, enables the biomimetic dosing of drugs in humans to be mimicked.