The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2016

Filed:

Mar. 29, 2012
Applicants:

Andreas Gschwind, Vienna, AT;

Rene Georg Ott, Vienna, AT;

Joachim Boucneau, De Pinte, BE;

Marie-ange Buyse, Merelbeke, BE;

Erik Depla, Destelbergen, BE;

Inventors:

Andreas Gschwind, Vienna, AT;

Rene Georg Ott, Vienna, AT;

Joachim Boucneau, De Pinte, BE;

Marie-Ange Buyse, Merelbeke, BE;

Erik Depla, Destelbergen, BE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/22 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); C07K 16/18 (2013.01); C07K 16/22 (2013.01); C07K 2317/22 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/569 (2013.01); C07K 2317/62 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

Bispecific binding molecules binding to both VEGF and Ang2, preferably in the form of immunoglobulin single variable domains like VHHs and domain antibodies, pharmaceutical compositions containing the same and their use in the treatment of diseases that are associated with VEGF- and/or Ang2-mediated effects on angiogenesis are disclosed. Further, nucleic acids encoding bispecific binding molecules, host cells and methods for preparing same are also described.


Find Patent Forward Citations

Loading…