The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
Oct. 02, 2015
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Merck Sharp & Dohme Ltd., Hoddesdon, GB;
Michael J. Zacuto, Jersey City, NJ (US);
Robert F. Dunn, Towaco, NJ (US);
Aaron J. Moment, Scotch Plains, NJ (US);
Jacob M. Janey, New York, NY (US);
David Lieberman, London, GB;
Faye Sheen, Hoddesdon, GB;
Nadine Bremeyer, Hoddesdon, GB;
Jeremy Scott, Hoddesdon, GB;
Jeffrey T. Kuethe, Somerset, NJ (US);
Lushi Tan, Edison, NJ (US);
Qinghao Chen, Edison, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Merck Sharp & Dohme Ltd., Hoddesdon, GB;
Abstract
A process for the preparation of pyrazolopyrolidines of structural formula I: and W is or P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process.