The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2016

Filed:

Dec. 19, 2012
Applicants:

Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, Jiangsu, CN;

Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Xuejun Zhang, Shanghai, CN;

Qing Dong, Shanghai, CN;

Bonian Liu, Shanghai, CN;

Yaoping Zhu, Shanghai, CN;

Xiaotao Li, Shanghai, CN;

Jiong Lan, Shanghai, CN;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C07D 471/04 (2006.01); A61K 31/437 (2006.01); C07D 217/06 (2006.01); C07D 221/04 (2006.01); C07D 209/44 (2006.01); C07D 209/52 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 45/06 (2013.01); C07D 209/44 (2013.01); C07D 209/52 (2013.01); C07D 217/06 (2013.01); C07D 221/04 (2013.01); C07D 403/04 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to a pyrrole six-membered heteroaryl ring derivative, the preparation method therefor, and the medicinal uses thereof. Specifically, the present invention relates to a new pyrrole six-membered heteroaryl ring derivative as represented by formula (I), the preparation method therefor, a medicinal composition comprising the derivative, and a therapeutic method using same, and, in particular, the uses as a JAK inhibitor and an immunosuppressor. Substituents in formula (I) have the same definitions as in the description.


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