The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
Aug. 14, 2012
Jianfeng LI, Shanghai, CN;
Guanghui Tian, Shanghai, CN;
Zhen Wang, Shanghai, CN;
Jin Suo, Shanghai, CN;
Xiangrui Jiang, Shanghai, CN;
Zheng Liu, Shanghai, CN;
Xiaojun Yang, Shanghai, CN;
Zhu Xie, Shanghai, CN;
Xianguo Zhao, Shanghai, CN;
Weiliang Zhu, Shanghai, CN;
Hualiang Jiang, Shanghai, CN;
Jingshan Shen, Shanghai, CN;
Jianfeng Li, Shanghai, CN;
Guanghui Tian, Shanghai, CN;
Zhen Wang, Shanghai, CN;
Jin Suo, Shanghai, CN;
Xiangrui Jiang, Shanghai, CN;
Zheng Liu, Shanghai, CN;
Xiaojun Yang, Shanghai, CN;
Zhu Xie, Shanghai, CN;
Xianguo Zhao, Shanghai, CN;
Weiliang Zhu, Shanghai, CN;
Hualiang Jiang, Shanghai, CN;
Jingshan Shen, Shanghai, CN;
TOPHARMAN SHANGHAI CO., LTD., Shanghai, CN;
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES TOPHARMAN SHANDONG CO., LTD, Shanghai, CN;
Abstract
The present invention relates to new salts of pyrazolopyrimidinone represented by formula (I), and pharmaceutically acceptable polymorph, solvate, hydrate, dehydrate, co-crystallization, anhydrous, or amorphous form thereof, the pharmaceutical compositions, and a pharmaceutical unit dosage form containing the same, wherein x represents organic or inorganic acids, preferable maleic acid, succinic acid, methanesulfonic acid, hydrochloric acid, etc. The invention further relates to co-crystals or complexes of compounds of pyrazolopyrimidinone and pharmaceutical compositions containing the same. The present invention also relates to a process for the preparation, use thereof and pharmaceutical preparation containing the salts or crystalline forms.