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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9527834 B1

PDFFull Text
Date of Patent:
Dec. 27, 2016

Filed:

Apr. 28, 2014

Substituted 1-benzylquinoxalin-2(1h)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor m1

Applicant:

Vanderbilt University, Nashville, TN (US);

Inventors:

Craig W. Lindsley, Brentwood, TN (US);

P. Jeffrey Conn, Nashville, TN (US);

Shaun R. Stauffer, Brentwood, TN (US);

Joseph David Panarese, Nashville, TN (US);

Assignee:

Vanderbilt University, Nashville, TN (US);

Attorney:

Michael Best & Friedrich LLP

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
A61K 31/498 (2006.01); C07D 241/44 (2006.01); C07D 403/10 (2006.01); A61K 9/00 (2006.01); A61K 47/36 (2006.01); A61K 9/10 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
C07D 403/10 (2013.01); A61K 9/0019 (2013.01); A61K 9/10 (2013.01); A61K 9/2018 (2013.01); A61K 47/36 (2013.01);
Abstract

The invention relates to substituted 1-benzylquinoxalin-2(1H)-one analogs, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M(mAChR M); methods for making the compounds; pharmaceutical compositions; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction. Exemplary 1-benzylquinoxalin-2(1H)-one compounds include compounds of the following formula:

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Quick Actions:

Lindsley, Craig. (2016). Substituted 1-benzylquinoxalin-2(1h)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor m1 (U.S. Patent No. 9527834). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9527834

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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