The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2016

Filed:

Feb. 25, 2016
Applicant:

Phyton Holdings, Llc, San Antonio, TX (US);

Inventors:

Brian A. Bucher, Boston, MA (US);

Edward M. Desimone, III, Indianapolis, IN (US);

Roland R. Franke, Gloucester, MA (US);

Rex T. Gallagher, Hampton, MA (US);

Barry J. Hand, Acton, MA (US);

Christopher D. Howe, Beverly, MA (US);

James H. Johnson, Edenton, NC (US);

John S. Juchum, Kingston, NH (US);

Marc A. Plante, Middleton, MA (US);

T. G. Sambandam, Uxbridge, MA (US);

Dong S. Yang, Quincy, MA (US);

Assignee:

Phyton Holdings, LLC, San Antonio, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 305/14 (2006.01); C07D 407/12 (2006.01);
U.S. Cl.
CPC ...
C07D 305/14 (2013.01); C07D 407/12 (2013.01);
Abstract

Disclosed is a method of crystallizing docetaxel comprising combining docetaxel and at least one solubilizing solvent to obtain a solution, wherein the solubilizing solvent is methylene chloride and adding an anti-solvent to the solution to obtain a crystalline docetaxel, wherein the anti-solvent is water.


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