The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
Sep. 06, 2013
Astellas Pharma Inc., Tokyo, JP;
Takashi Kikuchi, Tokyo, JP;
Shinya Yoshida, Tokyo, JP;
Atsushi Nakamura, Tokyo, JP;
Takahiro Akiba, Tokyo, JP;
Toshitaka Yoshino, Tokyo, JP;
Shuichi Nakagawa, Tokyo, JP;
Kiichi Sato, Tokyo, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
Provided are a method for producing a sulfonyl amidine compound, which has an excellent gonadotropin releasing hormone receptor antagonism and is useful as a therapeutic agent for gonadotropin-dependent diseases (for example, prostate cancer, breast cancer, endometriosis, uterine fibroid, prostatic hyperplasia, or the like) or a salt thereof, and a synthesis intermediate useful in the production method. The production method of the present invention controls formation of a by-product which is hardly removed unless column purification is conducted and racemization of a target compound, thereby obtaining the target compound with a high purity, and therefore, the production method is suitable for industrial production.