The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2016

Filed:

Mar. 22, 2012
Applicants:

Yu Huang, Shanghai, CN;

Ling Tong, DongGuan, CN;

Xueyan Zhu, Shanghai, CN;

Hanbin Shan, Gaoan, CN;

Zhedong Yuan, Shanghai, CN;

Xiong Yu, Hongkou District, CN;

Inventors:

Yu Huang, Shanghai, CN;

Ling Tong, DongGuan, CN;

Xueyan Zhu, Shanghai, CN;

Hanbin Shan, Gaoan, CN;

Zhedong Yuan, Shanghai, CN;

Xiong Yu, Hongkou District, CN;

Assignees:

LES LABORATOIRES SERVIER, Suresnes Cedex, FR;

SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY, Jing'an District, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 231/24 (2006.01); C07C 233/22 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
C07C 233/22 (2013.01); A61K 9/4866 (2013.01); C07C 231/24 (2013.01);
Abstract

The present invention provides a new crystalline form VII of agomelatine, its method of preparation, application and pharmaceutical composition. This new crystalline form offers high purity, a stable crystalline structure and good reproducibility, while its method of production lends itself well to large scale production. In terms of stability and purity, it is superior to the numerous crystalline forms which have hitherto been reported. As a result, the crystalline form VII of the present invention possesses advantages in pharmaceutical preparation.


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