The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
May. 19, 2015
Immunolight, Llc, Detroit, MI (US);
Duke University, Durham, NC (US);
Tuan Vo-Dinh, Chapel Hill, NC (US);
Jonathan P. Scaffidi, Durham, NC (US);
Venkata Gopal Reddy Chada, Durham, NC (US);
Benoit Lauly, Durham, NC (US);
Yan Zhang, Durham, NC (US);
Molly K. Gregas, Durham, NC (US);
Ian Nicholas Stanton, Durham, NC (US);
Joshua T. Stecher, Durham, NC (US);
Michael J. Therien, Durham, NC (US);
Frederic A. Bourke, Jr., Aspen, CO (US);
Harold Walder, Belville, NC (US);
Zak Fathi, Raleigh, NC (US);
Jennifer A. Ayres, Raleigh, NC (US);
Zhenyuan Zhang, Durham, NC (US);
Joseph H. Simmons, Tucson, AZ (US);
Stephen John Norton, Cary, NC (US);
Duke University, Durham, NC (US);
Immunolight, LLC, Detroit, MI (US);
Abstract
Products, compositions, systems, and methods for modifying a target structure. The methods may be performed in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength λ, to generate a second wavelength λof radiation having a higher energy than the first wavelength λ. The methods may further be performed by application of an initiation energy to activate a photoactivatable agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure.