The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
May. 21, 2013
Applicant:
The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);
Inventors:
Uday B. Kompella, Aurora, CO (US);
Rinku Baid, Aurora, CO (US);
Arun K. Upadhyay, Aurora, CO (US);
Sarath Yandrapu, Christianburg, VA (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE, Denver, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/475 (2006.01); A61K 47/48 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/18 (2013.01); A61K 47/48015 (2013.01); A61K 47/48884 (2013.01); C07K 14/475 (2013.01); A61K 38/00 (2013.01);
Abstract
LEDGF peptides with anti-protein aggregation activity and methods of use are provided. The LEDGF peptides disclosed herein demonstrate an ability to treat degenerative diseases and diseases with various cellular stresses including oxidative stress and protein-aggregation stress. In addition, extended release formulations, including formulations suitable for ophthalmic administration are provided.