The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
Mar. 16, 2011
Applicant:
Tariq M. Rana, San Diego, CA (US);
Inventor:
Tariq M. Rana, San Diego, CA (US);
Assignee:
Sanford-Burnham Medical Research Inslilute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/19 (2006.01); A61K 9/00 (2006.01); A61K 47/48 (2006.01); C12N 15/87 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 47/48038 (2013.01); A61K 47/48092 (2013.01); A61K 47/48323 (2013.01); C12N 15/87 (2013.01); C12N 2810/10 (2013.01);
Abstract
Provided are compositions and methods for delivery of therapeutic agents, such as chemically stabilized antisense oligonucleotides useful in RNA silencing. The compositions include interfering nanoparticles (iNOPs) associated with one or more agents. Several functional iNOP derivatives are provided which allow for targeted delivery of agents to specific cell types as well as exhibiting reduced cellular toxicity.