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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9523697 B1

PDFFull Text
Expired
Date of Patent:
Dec. 20, 2016

Filed:

Oct. 22, 2010

Detection of pathogenic abeta using an epitope protection assay

Applicants:

Neil Cashman, Vancouver, CA;

Marty Lehto, Burlington, CA;

Inventors:

Neil Cashman, Vancouver, CA;

Marty Lehto, Burlington, CA;

Assignee:

PROMIS NEUROSCIENCES Inc., Toronto, CA;

Attorneys:

Carmela De Luca

Bereskin & Parr LLP

Primary Examiner:

Chang-Yu Wang

Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 49/16 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); G01N 33/53 (2006.01); G01N 33/567 (2006.01); A61B 5/00 (2006.01); G01N 33/68 (2006.01); C07K 16/18 (2006.01); C07K 16/40 (2006.01); G01N 33/58 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); C07K 16/18 (2013.01); C07K 16/40 (2013.01); G01N 33/581 (2013.01); G01N 33/68 (2013.01); G01N 33/6845 (2013.01); A61K 38/00 (2013.01); G01N 2333/90283 (2013.01); G01N 2800/2828 (2013.01);
Abstract

The invention relates to an epitope protection assay for use in diagnosis, prognosis and therapeutic intervention in diseases, for example, involving polypeptide aggregation, such as prion infections. The methods of the invention first block accessible polypeptide target epitope with a blocking agent. After denaturation of the polypeptide, a detecting agent is used to detect protein with target epitope that was inaccessible during contact with the blocking agent.

Find Patent Forward Citations

Cashman, Neil. (2016). Detection of pathogenic abeta using an epitope protection assay (U.S. Patent No. 9523697). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9523697

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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