The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2016

Filed:

Mar. 02, 2011
Applicants:

Catherine Guette, La Possonniere, FR;

Olivier Coqueret, Angers, FR;

Benjamin Barre, Brain sur Longuenee, FR;

Erick Gamelin, Paris, FR;

Inventors:

Catherine Guette, La Possonniere, FR;

Olivier Coqueret, Angers, FR;

Benjamin Barre, Brain sur Longuenee, FR;

Erick Gamelin, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/574 (2006.01); A61K 31/4745 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 33/24 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C12Q 1/68 (2006.01); A61K 31/555 (2006.01); G01N 1/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57488 (2013.01); A61K 31/4745 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 31/555 (2013.01); A61K 33/24 (2013.01); A61K 39/395 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57419 (2013.01); C12Q 2600/118 (2013.01); G01N 2001/284 (2013.01);
Abstract

The present invention provides a method for diagnosing KRAS mutations in colorectal cancers by measuring the level of OLFM4. In another aspect, the present invention relates a method of predicting the responds to a chemotherapeutic agent of a subject suffering from a colorectal cancer: according to the present invention, the by determining the OLFM4 levels. According to the present invention, the response can be predicted by determining the OLFM4 levels. This result in turn permits the design or the adaptation of a treatment of the said subject with the said chemotherapeutic agent.


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