The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2016

Filed:

Jan. 17, 2014
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Jinsang Kim, Ann Arbor, MI (US);

Jiseok Lee, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/542 (2006.01); G01N 33/543 (2006.01); C07C 233/20 (2006.01); C07C 233/49 (2006.01); C07C 233/55 (2006.01); C07C 251/48 (2006.01); C07D 251/30 (2006.01); C07H 21/00 (2006.01); C40B 40/04 (2006.01); C40B 80/00 (2006.01); G01N 33/52 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5432 (2013.01); C07C 233/20 (2013.01); C07C 233/49 (2013.01); C07C 233/55 (2013.01); C07C 251/48 (2013.01); C07D 251/30 (2013.01); C07H 21/00 (2013.01); C40B 40/04 (2013.01); C40B 80/00 (2013.01); G01N 33/52 (2013.01); G01N 33/542 (2013.01); G01N 33/582 (2013.01); C07B 2200/11 (2013.01);
Abstract

A microarray includes a solid substrate having a surface, the surface having a plurality of binding spots and a plurality of reaction moieties bound to the binding spots. A reaction moiety includes a plurality of polyacetylene monomers, the polyacetylene monomers having a first coupling region and a second coupling region, the first coupling region having a first functional group operable to bind to the binding spot and the second coupling region comprising a second functional group operable to bind to an accessory molecule; and an accessory molecule having a binding region and an analyte reaction region, the analyte reaction region operable to selectively bind to the target analyte, and the binding region operable to bind to the second coupling region of the polyacetylene monomer. Upon binding a target analyte with the reaction moiety, a color change from the polyacetylene monomer occurs and the reaction moiety produces fluorescence.


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