The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2016

Filed:

Jun. 13, 2012
Applicants:

Naoto Uchida, Kanagawa, JP;

Hiroaki Goto, Kanagawa, JP;

Kazuhito Ohsawa, Kanagawa, JP;

Kohji Ohki, Kanagawa, JP;

Inventors:

Naoto Uchida, Kanagawa, JP;

Hiroaki Goto, Kanagawa, JP;

Kazuhito Ohsawa, Kanagawa, JP;

Kohji Ohki, Kanagawa, JP;

Assignee:

CALPIS CO., LTD., Tokyo, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); A61P 25/00 (2006.01); A61K 38/01 (2006.01); A61K 38/10 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01); A23C 9/12 (2006.01); A23C 9/13 (2006.01); A23J 3/32 (2006.01); A23J 3/34 (2006.01);
U.S. Cl.
CPC ...
C12P 21/06 (2013.01); A23C 9/1209 (2013.01); A23C 9/1307 (2013.01); A23J 3/325 (2013.01); A23J 3/344 (2013.01); A23L 33/18 (2016.08); A23L 33/19 (2016.08); A61K 38/018 (2013.01); A61K 38/10 (2013.01); A61K 38/1709 (2013.01); C07K 14/4732 (2013.01); C12Y 304/15 (2013.01); C12Y 304/15001 (2013.01); C12Y 304/15004 (2013.01); C12Y 304/16 (2013.01); C12Y 304/17 (2013.01); C12Y 304/17001 (2013.01); C12Y 304/21019 (2013.01); Y02P 20/52 (2015.11);
Abstract

The invention provides a method for preparing a peptide for improving brain function, comprising hydrolyzing milk casein with an enzymatic catalyst comprising a protease to produce a hydrolysate comprising: (i) a peptide consisting of the amino acid sequence shown in SEQ ID NO: 1 or a variant thereof; (ii) a peptide consisting of the amino acid sequence shown in SEQ ID NO: 2 or a variant thereof; or (iii) a mixture of the peptides of (i) and (ii), wherein the production yield of each of the peptides is 2% or more, or the total production yield of the mixture is 10% or more. The invention also provides a food or drink or a pharmaceutical composition containing the hydrolysate.


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