The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2016
Filed:
Nov. 08, 2013
Applicant:
Centre National DE LA Recherche Scientifique, Paris, FR;
Inventors:
Pierre-Alexandre Kaminski, Paris, FR;
Gilles Labesse, Montpellier, FR;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/10 (2006.01); C12N 9/24 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1077 (2013.01); C12N 9/2497 (2013.01); C12Y 204/02006 (2013.01);
Abstract
The present invention relates to enzyme mutants obtained from the nucleoside deoxyribosyltransferase (NDT) ofbacteria. These mutants are surprisingly able to exchange deoxyribose mono-, bi- and triphosphate between various nucleobases. In vitro syntheses have been successfully performed with several nucleobase analogs. These enzyme mutants provide new tools to synthesize, in vitro and/or in vivo, dNTPs or analogs thereof.