The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2016
Filed:
Mar. 31, 2011
Grant Gallagher, Milltown, NJ (US);
Raymond Yu, East Brunswick, NJ (US);
Joyce Eskdale, Milltown, NJ (US);
Jonathan Brazaitis, Parlin, NJ (US);
Grant Gallagher, Milltown, NJ (US);
Raymond Yu, East Brunswick, NJ (US);
Joyce Eskdale, Milltown, NJ (US);
Jonathan Brazaitis, Parlin, NJ (US);
Medical Diagnostic Laboratories, LLC, Hamilton, NJ (US);
Abstract
A naturally-occurring soluble truncated IL-23Rα protein (i.e., Δ9 IL-23Rα) is shown to be present in a biological sample and can serve as a diagnostic tool for autoimmune diseases. There is provided an enzyme-linked immunosorbent assay (ELISA) and test kit for the serological detection of the soluble truncated form of IL-23Rα protein. More particularly, antibody-sandwich ELISA method and kits for Δ9 IL-23Rα as an antigen were developed to detect Δ9 IL-23Rα levels in biological samples from a mammal and a human patient and are used as a diagnostic index. The present disclosed ELISA has utility as a diagnostic tool to detect Crohn's disease in patients using EDTA-plasma.