The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2016

Filed:

Sep. 11, 2013
Applicant:

Samsung Electronics Co., Ltd., Suwon-si, Gyeonggi-do, KR;

Inventors:

Jung-wook Lee, Yongin-si, KR;

Min-Kyung Kim, Seoul, KR;

Seon-hui Shim, Daegeon, KR;

Jae-il Lee, Yongin-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C07K 16/00 (2006.01); C07K 16/46 (2006.01); C07K 16/22 (2006.01); C07K 16/28 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); C07K 16/22 (2013.01); C07K 16/2863 (2013.01); C12P 21/02 (2013.01); C07K 2317/31 (2013.01); C07K 2317/569 (2013.01); C07K 2317/64 (2013.01); C07K 2319/02 (2013.01); C07K 2319/50 (2013.01); C07K 2319/70 (2013.01);
Abstract

A protein complex comprising (i) a first fusion protein comprising (a) a first polypeptide that comprises a first antigen-binding site and (b) a first binding protein linked to a terminus of the first polypeptide; and (ii) a second fusion protein comprising (a) a second polypeptide that comprises a second antigen-binding site and (b) a second binding protein linked to a terminus of the second polypeptide, wherein the protein complex comprises an amino acid sequence that enables cleavage between the first polypeptide and the first binding protein, and/or between the second polypeptide and the second binding protein, as well as a method for preparing a bi-specific antibody and related methods and compositions.


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