The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2016

Filed:

Jul. 23, 2014
Applicant:

Jeil Pharmaceutical Co., Ltd., Seoul, KR;

Inventors:

In-Hae Ye, Yongin-si, KR;

Chun-Ho Park, Yongin-si, KR;

Jong-Hee Choi, Suwon-si, KR;

Dong-il Kang, Yongin-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07C 53/06 (2006.01); C07C 55/10 (2006.01); C07C 55/14 (2006.01); C07C 57/145 (2006.01); C07C 57/15 (2006.01); C07C 59/245 (2006.01); C07C 59/255 (2006.01); C07C 229/24 (2006.01); C07C 307/02 (2006.01); C07C 309/04 (2006.01); C07C 309/19 (2006.01); C07C 309/29 (2006.01); C07D 239/22 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07C 53/06 (2013.01); C07C 55/10 (2013.01); C07C 55/14 (2013.01); C07C 57/145 (2013.01); C07C 57/15 (2013.01); C07C 59/245 (2013.01); C07C 59/255 (2013.01); C07C 229/24 (2013.01); C07C 307/02 (2013.01); C07C 309/04 (2013.01); C07C 309/19 (2013.01); C07C 309/29 (2013.01); C07D 239/22 (2013.01);
Abstract

The present invention relates to a novel crystalline acid salt of a tricyclic derivative or a hydrate thereof and a production method thereof. The crystalline acid salt or the hydrate thereof according to the present invention is stable with respect to humidity and stable with respect to hygroscopicity, and the quality control during manufacturing drugs is favorable. In addition, the crystalline acid salt or the hydrate thereof may be used in a pharmaceutical composition for preventing or treating neuropathic pain, epilepsy, stroke, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, schizophrenia, chronic and acute pain, ischemic brain injury, neuronal loss after hypoxia, trauma and nerve damage, which are medical conditions induced by PARP overactivity.


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