The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2016

Filed:

Dec. 07, 2012
Applicant:

Samyang Biopharmaceuticals Corporation, Seoul, KR;

Inventors:

Sa-Won Lee, Daejeon, KR;

Joong-Woong Cho, Daejeon, KR;

Gyeong-Hae Kim, Suwon-si, KR;

Min-Hyo Seo, Daejeon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2006.01); A61K 9/51 (2006.01); A61K 31/337 (2006.01); A61K 31/436 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/14 (2013.01); A61K 9/5146 (2013.01); A61K 31/337 (2013.01); A61K 31/436 (2013.01); A61K 9/5153 (2013.01);
Abstract

Disclosed are a polymeric drug carrier-containing pharmaceutical composition with enhanced stability in its solution state and a method for stabilizing the same. More particularly, disclosed are a pharmaceutical aqueous solution composition for storage under refrigeration containing a polymeric drug carrier comprising an amphiphilic block copolymer comprised of a hydrophilic block and a hydrophobic block, and a polylactic acid derivative fixed with a di- or tri-valent metal ion at its terminal carboxyl group and having preservation stability for at least 6 months, preferably at least 12 months when stored under refrigeration, and a method for stabilizing the same.


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