The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2016

Filed:

Jun. 03, 2015
Applicants:

Novartis Vaccines and Diagnostics Inc., Emeryville, CA (US);

Xoma Technology Ltd., Berkeley, CA (US);

Inventors:

Cheng Liu, Oakland, CA (US);

Deborah Lee Zimmerman, Oakland, CA (US);

Gregory Martin Harrowe, Eugene, OR (US);

Kirston Koths, El Cerrito, CA (US);

William Michael Kavanaugh, Orinda, CA (US);

Li Long, Lafayette, CA (US);

Maria Calderon-Cacia, Castro Valley, CA (US);

Arnold Horwitz, San Leandro, CA (US);

Assignees:

NOVARTIS VACCINES AND DIAGNOSTICS INC., Emeryville, CA (US);

XOMA TECHNOLOGY LTD., Berkeley, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/24 (2006.01); A61K 31/663 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/663 (2013.01); A61K 45/06 (2013.01); C07K 16/243 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

M-CSF-specific RX1-based or RX-1 derived antibodies are provided, along with pharmaceutical compositions containing such antibody, kits containing a pharmaceutical composition, and methods of preventing and treating bone loss in a subject afflicted with an osteolytic disease.


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