The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2016

Filed:

May. 29, 2012
Applicants:

Raimondo D'ambrosio, Seattle, WA (US);

Jason Fender, Bonney Lake, WA (US);

Jeffrey Ojemann, Seattle, WA (US);

John W. Miller, Bellevue, WA (US);

Matthew Smyth, Frontenac, MO (US);

Steven M. Rothman, Clayton, MO (US);

Inventors:

Raimondo D'Ambrosio, Seattle, WA (US);

Jason Fender, Bonney Lake, WA (US);

Jeffrey Ojemann, Seattle, WA (US);

John W. Miller, Bellevue, WA (US);

Matthew Smyth, Frontenac, MO (US);

Steven M. Rothman, Clayton, MO (US);

Assignees:

University of Washington, Seattle, WA (US);

Washington University, St. Louis, MO (US);

Regents of the University of Minnesota, Minneapolis, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 7/12 (2006.01); A61F 7/00 (2006.01); A61F 7/02 (2006.01);
U.S. Cl.
CPC ...
A61F 7/12 (2013.01); A61F 2007/0002 (2013.01); A61F 2007/0096 (2013.01); A61F 2007/0247 (2013.01);
Abstract

Passive prosthetic devices for focally cooling a brain and methods for inhibiting seizures are disclosed. The prosthetic devices replace a thermally insulating bone flap with a thermally conductive insert having an inner surface that contacts the relatively warm meninges or brain and an outer surface that contacts the relatively cool scalp. In an embodiment, the prosthesis is unitary; in another, a biocompatible casing is filled with a highly conductive core; in another, a filled polymer block is attached to a plate; and in another, the bone flap is filled with a conductive polymer. In one embodiment, a filled polymer containing elements that exhibit the magnetocaloric effect provide heat transfer that can be enhanced by application of a suitable magnetic field. Focal cooling as low as 1.2° C. has been found effective at inhibiting seizures.


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