The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2016

Filed:

Feb. 06, 2015
Applicant:

International Business Machines Corporation, Armonk, NY (US);

Inventors:

Binquan Luan, Chappaqua, NY (US);

Ruhong Zhou, Stormville, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 27/447 (2006.01); G01N 27/453 (2006.01); B82Y 30/00 (2011.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); G01N 27/447 (2013.01); G01N 27/44791 (2013.01); G01N 27/453 (2013.01); B82Y 5/00 (2013.01); B82Y 30/00 (2013.01); Y10S 977/742 (2013.01); Y10S 977/781 (2013.01); Y10S 977/924 (2013.01);
Abstract

A mechanism is provided for ratcheting a double strand molecule. The double strand molecule is driven into a Y-channel of a membrane by a first voltage pulse. The Y-channel includes a stem and branches, and the branches are connected to the stem at a junction. The double strand molecule is slowed at the junction of the Y-channel based on the first voltage pulse being weaker than a force required to break a base pair of the double strand molecule. The double strand molecule is split into a first single strand and a second single strand by driving the double strand molecule into the junction of the Y-channel at a second voltage pulse.


Find Patent Forward Citations

Loading…