The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2016
Filed:
Nov. 10, 2010
Matteo Negroni, Strasbourg, FR;
Sarah Gallois-montbrun, Ville d'Avray, FR;
Paola Rossolillo, Strasbourg, FR;
Vincenzo Di Bartolo, Antony, FR;
Gilles Uze, Montpellier, FR;
Etienne Simon-loriere, State College, PA (US);
Roland Marquet, Illkirch-Graffenstaden, FR;
Valérie Vivet-boudou, Strasbourg, FR;
Matteo Negroni, Strasbourg, FR;
Sarah Gallois-Montbrun, Ville d'Avray, FR;
Paola Rossolillo, Strasbourg, FR;
Vincenzo Di Bartolo, Antony, FR;
Gilles Uze, Montpellier, FR;
Etienne Simon-Loriere, State College, PA (US);
Roland Marquet, Illkirch-Graffenstaden, FR;
Valérie Vivet-Boudou, Strasbourg, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), Paris, FR;
Abstract
A method of directing evolution of a target polynucleotide of interest for obtaining variants of this target polynucleotide, a method to generate genetic variability by preparing a cell library, and a method to isolate or to screen variants of a polynucleotide or variants of a protein able to impact the phenotype of a cell or to confer a desired phenotype to target cells, and to identify theses polynucleotide variants or protein variants responsible for this phenotype are described.