The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2016

Filed:

May. 22, 2013
Applicants:

Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);

Christopher K. Glass, San Diego, CA (US);

Michael G. Rosenfeld, San Diego, CA (US);

Wenbo LI, San Diego, CA (US);

Michael T. Lam, La Jolla, CA (US);

Inventors:

Susan M. Freier, San Diego, CA (US);

Christopher K. Glass, San Diego, CA (US);

Michael G. Rosenfeld, San Diego, CA (US);

Wenbo Li, San Diego, CA (US);

Michael T. Lam, La Jolla, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01); C12N 15/113 (2010.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/85 (2013.01); C12N 2310/11 (2013.01); C12N 2310/113 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/341 (2013.01);
Abstract

Disclosed herein are methods and compounds for inhibiting gene expression by inhibiting enhancer RNAs (eRNAs). Such methods and compounds are useful for reducing expression of certain genes, many of which are associated with a variety of diseases and disorders.


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