The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2016

Filed:

Feb. 28, 2013
Applicant:

Benitec Biopharma Limited, Balmain, New South Wales, AU;

Inventors:

Peter William French, Balmain, AU;

Michael Wayne Graham, Jindalee, AU;

Assignee:

Benitec Biopharma Limited, Balmain, New South Wales, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/1137 (2013.01); C12Y 104/03003 (2013.01); C12Y 207/11013 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/51 (2013.01); C12N 2310/531 (2013.01);
Abstract

The disclosure relates to an RNA interference (RNAi) agent and the use of that RNAi agent to treat chronic pain in individuals, as well as pharmaceutical compositions containing the RNAi agents of the invention. The DNA-directed RNA interference (ddRNAi) agent for inhibiting expression of one or more target sequences in a pain associated gene comprises, one or more effector sequence sequences and effector complement sequences of at least 17 nucleotides in length, wherein the effector sequence is substantially complementary to the predicted transcript of a target sequence within a pain associated gene.


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