The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2016
Filed:
Jun. 15, 2011
Frank Rigo, Carlsbad, CA (US);
C. Frank Bennett, Carlsbad, CA (US);
Adrian R. Krainer, Huntington Station, NY (US);
Yimin Hua, Jericho, NY (US);
Frank Rigo, Carlsbad, CA (US);
C. Frank Bennett, Carlsbad, CA (US);
Adrian R. Krainer, Huntington Station, NY (US);
Yimin Hua, Jericho, NY (US);
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Provided herein are antisense compounds and methods for recruiting one or more non-cleaving protein to a target nucleic acid in a cell. In certain instances such recruitment of a non-cleaving protein alters the function or activity of the target nucleic acid. In certain such instances, the target nucleic acid a pre-mRNA and the recruitment of the non-cleaving protein results in a change in splicing of the pre-mRNA.