The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2016

Filed:

Mar. 18, 2016
Applicant:

Gwo Xi Stem Cell Applied Technology Co., Ltd., Zhubei, Hsinchu County, TW;

Inventors:

Shinn-Zong Lin, Zhubei, TW;

Horng-Jyh Harn, Zhubei, TW;

Ru-Huei Fu, Zhubei, TW;

Shih-Ping Liu, Zhubei, TW;

Po-Cheng Lin, Zhubei, TW;

Ming-Hsi Chuang, Zhubei, TW;

Assignee:

GWO XI STEM CELL APPLIED TECHNOLOGY CO., LTD., Zhubei, Hsinchu County, TW;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/0775 (2010.01); A61K 35/545 (2015.01); A61K 35/28 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0667 (2013.01); A61K 35/28 (2013.01); A61K 35/545 (2013.01); C12N 2501/40 (2013.01);
Abstract

A method for enhancing the therapeutic effect of stem cells on autoimmune diseases, cardiovascular diseases, and/or hematological diseases is provided. The method comprises pre-treating the stem cells with ligustilide to increase the expression of differentiation-promoting genes in the stem cells, increase the expression of homing-promoting genes in the stem cells, and/or decrease the expression of inflammatory genes in the stem cells, wherein the treatment is conducted in a culture medium of the stem cell.


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