The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2016
Filed:
Nov. 11, 2011
Ruben Claudio Aguilar, West Lafayette, IN (US);
Timothy Ratliff, West Lafayette, IN (US);
David Thompson, West Lafayette, IN (US);
Scott Crist, West Lafayette, IN (US);
Ruben Claudio Aguilar, West Lafayette, IN (US);
Timothy Ratliff, West Lafayette, IN (US);
David Thompson, West Lafayette, IN (US);
Scott Crist, West Lafayette, IN (US);
Purdue Research Foundation, West Lafayette, IN (US);
Abstract
Composition and methods are disclosed for utilizing micro-aggregation of FAP-containing complexes to promote their fast internalization. This approach allows the uptake of cytotoxic cargo coupled to either FAP-Antibodies or FAP-liposome complexes by tumor bladder cells. Importantly, this approach is efficient even under serum-free conditions such as the ones found in the lumen of the bladder.