The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2016

Filed:

Jun. 17, 2015
Applicants:

President and Fellows of Harvard College, Cambridge, MA (US);

The Governors of the University of Alberta, Edmonton, CA;

Inventors:

Adam E. Cohen, Cambridge, MA (US);

Daniel Hochbaum, Cambridge, MA (US);

Peng Zou, Cambridge, MA (US);

Samouil Leon Farhi, Cambridge, MA (US);

Robert Earl Campbell, Edmonton, CA;

Yongxin Zhao, Edmonton, CA;

Daniel Jed Harrison, Edmonton, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); C07K 14/705 (2006.01); G01N 33/566 (2006.01); C07K 14/215 (2006.01);
U.S. Cl.
CPC ...
C07K 14/705 (2013.01); C07K 14/215 (2013.01); G01N 21/6428 (2013.01); G01N 33/566 (2013.01); G01N 2021/6441 (2013.01); G01N 2333/726 (2013.01);
Abstract

Provided herein are variants of an archaerhodopsin useful for application such as optical measurement of membrane potential. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, cells comprising the polynucleotides, and cells comprising the polypeptides; and methods of using the variants.


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