The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2016
Filed:
Nov. 02, 2015
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Paul S. Charifson, Framingham, MA (US);
Michael P. Clark, Concord, MA (US);
Upul K. Bandarage, Lexington, MA (US);
Randy S. Bethiel, Lexington, MA (US);
John J. Court, Littleton, MA (US);
Hongbo Deng, Southborough, MA (US);
Ioana Davies, Arlington, MA (US);
John P. Duffy, Northborough, MA (US);
Luc J. Farmer, Montreal, CA;
Huai Gao, Arlington, MA (US);
Wenxin Gu, Concord, MA (US);
Dylan H. Jacobs, South Boston, MA (US);
Joseph M. Kennedy, Charlestown, MA (US);
Mark W. Ledeboer, Acton, MA (US);
Brian Ledford, Norton, MA (US);
Francois Maltais, Tewksbury, MA (US);
Emanuele Perola, Brookline, MA (US);
Tiansheng Wang, Concord, MA (US);
M. Woods Wannamaker, Stow, MA (US);
Randal Byrn, Wayland, MA (US);
Yi Zhou, Lexington, MA (US);
Chao Lin, Winchester, MA (US);
Min Jiang, Lexington, MA (US);
Steven Jones, Hyde Park, MA (US);
Ursula A. Germann, Newton, MA (US);
Francesco G. Salituro, Marlborough, MA (US);
Ann Dak-Yee Kwong, Cambridge, MA (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.